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Highly regarded by both students and instructors, Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 5th Edition, provides a unique, integrated mechanism-based and systems-based approach to contemporary pharmacology and drug development. An easy-to-follow format helps both undergraduate and graduate students grasp challenging concepts quickly and efficiently. Each chapter presents a clinical vignette illustrating a therapeutic problem within a physiologic or biochemical system; followed by a discussion of the biochemistry, physiology, and pathophysiology of the system; and concluding with a presentation of the pharmacology of the drugs and drug classes that activate or inhibit the system by interacting with specific molecular and cellular targets.
Selected as a Doody's Core Title for 2022 and 2023! Known for generations as the most comprehensive foundational text on medical microbiology, Schaechter's Mechanisms of Microbial Disease delivers a thorough understanding of microbial agents and the pathophysiology of microbial diseases. This trusted text is universally praised for "telling the story of a pathogen" in an engaging way, facilitating learning and recall by emphasizing unifying principles and paradigms. Content is uniquely organized by microbial class and by organ system, making it equally at home in traditional and systems-based curricula. This updated 6th Edition reflects the latest advances in the field, including significant enhancements to the coverage of serious threats to global health such as COVID-19, respiratory and childhood viruses, and sexually transmitted diseases. New illustrations and additional learning features further clarify concepts, reinforce understanding, and help users confidently prepare for board exams and beyond.